After graduating from the medical faculty of the Tomsk Medical Institute, clinical residency at the Department of Otorhinolaryngology, E.L. Choinzonov was invited to the position of junior researcher at the Department of Head and Neck Tumors in the Siberian Branch of the All-Union Cancer Research Center of the USSR Academy of Medical Sciences. In 1984, having successfully defended his Ph.D. thesis on the topic: "Treatment of patients with oral cancer and its impact on the parameters of the immune system", he was transferred to the position of senior researcher.
After defending his doctoral thesis in 1995 on the topic: "Cancer of the upper respiratory and digestive tract (epidemiological and immunovirological aspects, evaluation of the effectiveness of treatment)" he became a leading researcher in the same department of the Research Institute of Oncology. In 2002, he was awarded the title of professor in the specialty "oncology". In 2005, he was elected a corresponding member of the Russian Academy of Medical Sciences with a degree in Oncology, and in 2011 - an academician of the Russian Academy of Medical Sciences. From 2002 to June 30, 2016 - Director of the Tomsk Research Institute of Oncology, from July 1, 2016 - December 14, 2018 - Director of the Tomsk Research Medical Center, from December 19, 2018 - Director of the Research Institute of Oncology of the Tomsk Research Medical Center.
Area of scientific interests
E.L. Choinzonov is the author of more than 1000 published works, including 30 monographs, 1 manual for doctors, 1 methodological manual, 13 clinical recommendations, 337 Russian and foreign articles. He has 53 patents for inventions and 21 certificates of state registration of software products, 5 license agreements. Under his leadership, 16 doctoral and 21 master's theses were completed and defended.
The main areas of scientific activity of Choinzonov E.L. are connected with the development of methods for early diagnosis, organ-preserving and reconstructive-plastic surgical treatment, combination therapy, rehabilitation of patients with malignant neoplasms of the head and neck region, the study of the mechanisms of carcinogenesis and tumor progression.
In order to increase the effectiveness of treatment and functional results in patients with malignant neoplasms of the maxillofacial region and larynx, he developed and introduced into clinical practice original surgical operations using simultaneous replacement of postoperative defects with endoprostheses made of porous titanium nickelide and microsurgical tissue autotransplantation. New approaches to the treatment of cancer of the thyroid, parotid glands, nasal cavity and paranasal sinuses based on organ-preserving operations in combination with intraoperative electron and remote neutron therapy are proposed.
Modern methodological approaches have been developed to restore the voice-forming function in patients after combined therapy for cancer of the larynx, oral cavity and oropharynx, with paresis and paralysis of the larynx using biofeedback based on mathematical modeling. Fundamental problems developed under the guidance of Choinzonov E.L. relate to the study of the role of the immune system and oncogenic viruses in the genesis of tumor growth. New information about the mechanisms of formation of resistance of tumor cells to free radical damage has been obtained, clinical and epidemiological features of primary multiple tumors of the head and neck have been revealed.